Immunobiosensor development for monitoring of pesticides and their transformation products

Country: EU Projects
Start Date:   1/1/1994         Duration: 24 months         Project Type: RTD
Contract Number: EV5V-CT930354
Organisation Type:  University research group / research institute
Contaminated land-->Site investigation-->Methods
Diffuse pollution-->Diffuse pollution overview
Diffuse pollution-->Monitoring
Project objectives:
The project aimed to develop immunochemical detection techniques to allow the fast screening of pesticides  and transformation products in acuqatic environmental 
matricies by using commercially available antibodies against specified pesticides.
Project Summary:
As no continuous flow on-line immunobiosensors were available at the time of the project, three different experimental methodologies were developed, varying 
thetypes of antibodies used, principles and limits of detection, ease of use and regeneration requirements. The three methods tested were: surface plasma
resonance detection using non-labelled antibodies; fluorescence detection using fluorescein-labelled antibodies; amperometric detection using enzyme
labeled antibodies. The immunbiosensors were implemented in flow injection analysis systems to allow contimuous, automated processing of samples. Non-biological
analysis was used as a means of quality control over the results.
Achieved Objectives:

Product Descriptions:

Additional Information:
Lead Institution: 
Rijksuniversiteit Leiden, Leiden, NL  
Partner Institutions: 
Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Oonderzoek, Zeist, NL Consejo Superior de Investigaciones Cientificas, Barcelona, 
Spain Universidad de Alcala de Henares, Alcala de Henares, Spain Lunds Uuiversiteit, Lund, SE This information was taken from a source other than the project site: European Commission (1994) Environment Research Programme, Catalogue of Contracts
1992-1994: Technologies and Engineering for the Environment. ISBN 92-826-8280-3
Project Resources:
Funding Programme(s): 
EC Framework 4 Funding Programme FP4 of European Community activities in the field of research and technological development and demonstration
Link to Organisations:
Submitted by: EUGRIS Team Dr Antony Chapman  Who does what?  18/11/2005 12:33:00
Updated by: EUGRIS Team Professor Paul Bardos  Who does what?  28/09/2006 17:37:00