Title: Multianalyte determination of different classes of pesticides (acidic, triazines, phenyl ureas, anilines, organophosphates, molinate and propanil) by liquid chromatography-electrospray-tandem mass spectrometry 
Resource Type: document --> technical publication --> journal article 
Country: EU Projects 
Year: 2004 
Availability: Borba da Cunha, Ana C et al. (2004) Multianalyte determination of different classes of pesticides (acidic, triazines, phenyl ureas, anilines, organophosphates, molinate and propanil) by liquid chromatography-electrospray-tandem mass spectrometry 
Author 1/Producer: Borba da Cunha, Ana C 
Other Authors/Producers: López de Alda, Maria J. Barceló, Damià Pizzolato, Tania M. dos Santo, Joao Henrique Z 
Author / Producer Type: EC Project 
Article Weblink (=direct link): http://projects.dhi.dk/artdemo/Publications/Borba%20de%20Cun ...  
Format (e.g. PDF): PDF 
EUGRIS Keyword(s): Contaminated land-->Contaminants-->Contaminants overview
 
Short description: This work describes the optimization of a liquid chromatography-electrospray-tandem mass spectrometry (LC-ESI-MS-MS) method for the multianalyte determination of twenty pesticides, selected based on current regulations and extent of use. Chromatographic separation was carried out on a Purospher STAR RP-18e column using gradient acetonitrile-water as mobile phase. Triazines, phenylureas, organophosphates, anilines, and molinate were determined in the positive ionization mode, and acidic pesticides and propanil in the negative ion mode. Two different precursor ion-product ion transitions were selected for each analyte and monitored under time scheduled multiple reaction monitoring (MRM) conditions. The optimized method was shown to be linear in the range 1 to 1000 ng/mL with correlation coefficients higher than 0.99 for all but one (diazinon) of the analytes, very sensitive (with limits of detection between 0.010 and 4.528 ng/mL), and repeatable (with relative standard deviations, calculated from the replicate analysis of standard mixtures, lower than 14%). The present work was also devoted to the elucidation of the structures of the principal fragment ions obtained after collision-induced dissociation of the pesticides investigated, an aspect often overlooked in the literature. 
Link to Project(s): ARTDEMO Artificial recharge demonstration project
 
Submitted By: Dr Stefan Gödeke WhoDoesWhat?      Last update: 14/02/2006