Title: Stimulated embryo production as a parameter of estrogenic exposure via sediments in the freshwater mudsnail Potamopyrgus antipodarum. 
Resource Type: document --> technical publication --> journal article 
Country: EU Projects 
Year: 2003 
Availability: Duft M, Schulte-Oehlmann U, Weltje L, Tillmann M, Oehlmann J (2003): Stimulated embryo production as a parameter of estrogenic exposure via sediments in the freshwater mudsnail Potamopyrgus antipodarum. Aquat. Toxicol. 64, 437-449 
Author 1/Producer: Duft M 
Other Authors/Producers: Schulte-Oehlmann U, Weltje L, Tillmann M, Oehlmann J 
Author / Producer Type: EC Project 
Article Weblink (=direct link): http://www.comprendo-project.org/_files/Potamopyrgus-AquatTo ...  
Format (e.g. PDF): PDF 
EUGRIS Keyword(s): Contaminated land-->Contaminants-->Contaminants overview
 
Short description: The xeno-estrogens BPA, OP and NP caused distinct increases in the embryo production and the total embryo number in P. antipodarum mostly already at the lowest applied concentrations. Evaluating the results for the tested substances, we can conclude that the chronic effects on P. antipodarum and their intensity are comparable and in good accordance with the experiments of Oehlmann et al. (2000) and Schulte-Oehlmann et al. (2000). In the presence of BPA and OP where we found sharper increases of the embryo numbers and lower effect concentrations (LOEC, EC10 and EC50), the reproductive performance was stimulated to a greater extent than at exposure to NP. There was no acute toxicity in the conducted experiments. Our results show that P. antipodarum is highly sensitive to the xeno-estrogens BPA, OP and NP in the sediment at environmentally relevant concentrations. Finally, it can be concluded that the sediment bioassay with P. antipodarum represents a promising system for the identification of endocrine disrupting substances and offers the more general possibility as tool for the assessment of sediment quality. 
Link to Project(s): COMPRENDO Comparative Research on Endocrine Disrupters - Phylogenetic Approach and Common Principles focussing on Androgenic/Antiandrogenic Compounds
 
Submitted By: Dr Stefan Gödeke WhoDoesWhat?      Last update: 14/02/2006